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KMID : 0043320090320091227
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Archives of Pharmacal Research
2009 Volume.32 No. 9 p.1227 ~ p.1231
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A Cyclohexenone Derivative from Diaporthaceous Fungus PSU-H2
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Vatcharin Rukachaisirikul
Ubonta Sommart
Yaowapa Sukpondma
Souwalak Phongpaichit
Nongporn Hutadilok Towatana
Potchanapond Graidist
Zuboidah Hajiwangoh
Jariya Sakayaroj
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Abstract
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One new cyclohexenone derivative (1) was isolated from Diaporthaceous fungus PSU-H2 together with six known compounds, dothiorelone A (2), dothiorelone C (3), 2,3-dihydromycoepoxydiene (4), (+)-mycoepoxydiene (5), deacetylmycoepoxydiene (6) and tyrosol (7). The structures were elucidated by spectroscopic methods. Their cytotoxic activity against human breast cancer cell line, MCF-7, was evaluated.
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KEYWORD
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Diaporthaceae, Endophytic fungus, Cyclohexenone, Mycoepoxydiene, Dothiorelone, Cytotoxic activity
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